프로슈머,건강정보,소비자의 힘

Purine Nucleoside Phosphorylase 이미지

장백산-1 2009. 4. 29. 21:08
설명
English:

Computer-generated Model of Purine Nucleoside Phosphorylase (PNP)

Purine Nucleoside Phosphorylase (PNP) is an important target enzyme for the design of anti-cancer and immunosuppressive drugs. Bacterial PNP, which is slightly different from the human enzyme, is used to synthesize chemotherapeutic agents. Knowledge of the three-dimensional structure of the bacterial PNP molecule is useful in efforts to engineer different types of PNP enzymes, that can be used to produce new chemotherapeutic agents. This picture shows a computer model of bacterial PNP, which looks a lot like a display of colorful ribbons. Principal Investigator was Charles Bugg.